澳门大阳城集团2138网站|主頁-欢迎您!

ENGLISH

检测到您当前使用浏览器版本过于老旧,会导致无法正常浏览网站;请您使用电脑里的其他浏览器如:360、QQ、搜狗浏览器的极速模式浏览,或者使用谷歌、火狐等浏览器。

下载Firefox
童梦莎助理教授

邮  箱:mstong@xmu.edu.cn

职称/职务:助理教授

联系方式:

  • 个人简介
  • 科研领域
  • 代表性成果

2013年,福建医科大学药学专业,学士学位;
2016年,福建医科大学生物信息专业,硕士学位;
2019年,清华大学生物信息专业,博士学位;
2019年,澳门大阳城集团澳门大阳城集团2138网站,助理教授;
2021年,澳门大阳城集团澳门大阳城集团2138网站,特任副研究员。
B.S. 2013, Fujian Medical University, Pharmacy;
M.S. 2016, Fujian Medical University, Bioinformatics;
Ph.D. 2019, Tsinghua University, Bioinformatics;
Assistant Professor, School of Life Sciences, Xiamen University, 2019 to Present.

主要从事肿瘤生物信息转化医学研究,具体内容如下:
(1)利用生物信息学技术分析多维组学数据(基因组/转录组/表观基因组/单细胞转录组/单细胞质谱成像等),筛选肿瘤分子标志物与药物靶点
(2)肿瘤蛋白质组和磷酸化组质谱数据个体化分析
(3)蛋白质修饰功能预测
(1)Using bioinformatics technology to identify cancer biomarkers and drug targets based on multi-omics data (genome; transcriptome; epigenome; sc-RNAseq; IMC)
(2) Individualized analysis of cancer proteome and phosphoproteome
(3) Functional prediction of protein modifications

代表性论文(# co-first author, * Corresponding author):

1.Yachen Liu , Yalan Lin, Yuxiang Lin, Yujuan,Wu, Zheyang Zhang, Nuoqi Lin, Xianlong Wang, Mengsha Tong*, Rongshan Yu*. Application of individualized differential expression analysis in human cancer proteome. Briefings in Bioinformatics, 2022 Apr 2;bbac096.
2.Mengsha Tong#; Chunyu Yu#; Jinwen Shi#; Wenwen Huang#; Sai Ge#; Mingwei Liu; Lei;Song; Dongdong Zhan; Xia Xia;Wanlin Liu; Jinwen Feng; Wenhao Shi;Jiafu Ji; Jing Gao; Tieliu Shi; Weimin Zhu;Chen Ding; Yi Wang; Fuchu He*; Lin Shen*; Tingting Li*; Jun Qin*; Phosphoproteomics Enables Molecular Subtyping and Nomination of Kinase Candidates for Individual Patients of Diffuse-Type Gastric Cancer, iScience, 2019, 22: 44–57.
3.Mengsha Tong#; Chunyu Yu #; Dongdong Zhan; Ming Zhang; Bei Zhen; Weimin Zhu; Yi Wang; Congying Wu; Fuchu He*; Jun Qin*; Tingting Li*; Molecular subtyping of cancer and nomination of kinase candidates for inhibition with phosphoproteomics: reanalysis of CPTAC ovarian cancer, EBioMedicine, 2018, 40 (2352-3964): 305-317.
4.Mengsha Tong#; Weicheng Zheng#; Hongdong Li; Xiangyu Li; Lu Ao; Yifeng Shen; Qirui Liang; Jing Li; Guini Hong; Haidan Yan; Hao Cai; Mengyao Li; Qingzhou Guan; Zheng Guo*; Multi-omics landscapes of colorectal cancer subtypes discriminated by an individualized prognostic signature for 5-fluorouracil-based chemotherapy, Oncogenesis, 2016, 5(2157-9024).
5.Yifeng Shen#; Mengsha Tong#; Qirui Liang; Huaqin Sun; Weicheng Zheng; Lu Ao; Zheng Guo*; Feifei She*; Epigenomics alternations and dynamic transcriptional changes in responses to 5-fluorouracil stimulation reveal mechanisms of acquired drug resistance of colorectal cancer cells, The Pharmacogenomics Journal 2017, 18 (1470-269X): 23-28.
6.GaiGai Guo, Zhouyong Gao, Mengsha Tong, Dongdong Zhan, Guangshun Wang, Yi Wang, Jun Qin*. NQO1 is a determinant for cellular sensitivity to anti-tumor agent. Napabucasin American Journal of Cancer Research 2020; 10(5):1442-1454

荣誉、奖励及参加学术团体的情况:

福建省引进高层次人才(国内B类)
厦门市高层次人才(C类)
福建省生物信息学学会 办公室主任